Outcome After Lung Volume Reduction Surgery in Patients With Severely Impaired Diffusion Capacity

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Lung Volume Reduction Surgery in Patients with Copd

Emphysema is a progressive and debilitating disease associated with a high rate of morbidity and mortality as a result of respiratory failure. Medical therapy and pulmonary rehabilitation are useful palliative treatment options and can temporarily improve symptoms. However, they do not alter much the natural history of the disease. Endstage emphysema markedly limits the quality of life and surv...

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Lung volume reduction surgery.

Background. Surgery to reduce lung volume has recently been reintroduced to alleviate dyspnea and improve exercise tolerance in selected patients with emphysema. A reliable means of identifying patients who are likely to benefit from this surgery is needed. Methods. We measured lung resistance during inspiration, static recoil pressure at total lung capacity, static lung compliance, expiratory ...

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Changes in ventilatory mechanics and diaphragmatic function after lung volume reduction surgery in patients with COPD.

BACKGROUND Lung volume reduction (LVR) has recently been used to treat severe emphysema. About 25% of the volume of each lung is removed with this method. Little is known about the mechanism of functional improvement so a study was undertaken to investigate the changes in ventilatory mechanics and diaphragmatic function in eight patients after LVR. METHODS Measurements of work of breathing (W...

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Diaphragm length and neural drive after lung volume reduction surgery.

RATIONALE Patients with chronic obstructive pulmonary disease have shorter inspiratory muscles and higher motor unit firing rates during quiet breathing than do age-matched healthy subjects. Lung volume reduction surgery (LVRS) in patients with chronic obstructive pulmonary disease improves lung function, exercise capacity, and quality of life. OBJECTIVES We studied the effect of LVRS on leng...

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Development of a giant bulla after lung volume reduction surgery.

Lung volume reduction surgery (LVRS) is being evaluated in the treatment of emphysema. The proposed mechanisms of improvement are increased elastic recoil of the lung and improved mechanical efficiency of the muscles of respiration. We report a unique patient with emphysema who developed a giant bulla 3 years subsequent to LVRS. The patient underwent extensive evaluation, including measurements...

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ژورنال

عنوان ژورنال: The Annals of Thoracic Surgery

سال: 2018

ISSN: 0003-4975

DOI: 10.1016/j.athoracsur.2017.09.006